"I believe more fiercely than ever that citizen engagement at every level is central to a strong and vibrant democracy," Clinton said announcing the launch of her group 'Onward Together'.
"More than ever, I believe citizen engagement is vital to our democracy. I'm so inspired by everyone stepping up to organise and lead," the former Secretary of State, said to her supporters as she urged them to contribute to the "remarkable" spirit of political activism.
The announcement comes as Clinton, 69, works to find a new role in an evolving political landscape.
The new group's website said it aimed to advance progressive values and reminded visitors that Clinton had won nearly 66 million votes in November's showdown with Trump.
"Onward Together will work to build a brighter future for generations to come by supporting groups that encourage people to organise and run for office," wrote the former Secretary of State.
Clinton becomes the latest high-profile Democrat to launch an independent group. Former President Barack Obama, Vermont Sen. Bernie Sanders, and 2004 Democratic nominee Howard Dean all helped create political organisations.